Pietro Scaturro

The paper identifies apolipoprotein C1 as a host factor that facilitates HBV and HDV infection by associating with viral particles and enhancing infectivity through SR-B1.

This study identifies conserved interactions of NS4B with the UFMylation pathway across orthoflaviviruses, revealing a novel role for UFMylation in viral replication and suggesting it as a therapeutic target.

This study identifies ATL2 as critical for flavivirus replication by organizing viral replication organelles and limiting immune activation.

This study identifies ephrin B1 as a host factor mediating dengue virus NS1-induced endothelial barrier dysfunction and shows EFNB1-Fc fusion proteins can block this effect.

This study develops a zebrafish model of Zika virus infection and identifies NS4A as a key factor in neuropathogenesis through transcriptomic and morphological analyses.

This study identifies IGF2BP2 as a host factor hijacked by ZIKV to regulate viral replication organelle biogenesis and vRNA synthesis.

Concurrent multi-omics of SARS-CoV-2 and SARS-CoV in A549 cells, integrated by network diffusion, maps shared and virus-specific host perturbations and nominates antiviral drug hotspots.