Author

Naseem Sadek

Emory University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Jeffrey Alan Tomalka· 3 shared Adolfo García‐SastreiD· 1 shared Adriana TomićiD· 1 shared Ahmet F. CoskuniD· 1 shared Alba EscaleraiD· 1 shared Andrew John PollardiD· 1 shared Brandon F. KeeleiD· 1 shared Bruno G. De GeestiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersImmunology

Jeffrey Alan Tomalka

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Interleukin-6 restricts pre-thymic T cell lineage commitment of progenitors driving loss of SIV control

Saleem Anwar, Naseem Sadek, Christian Michel Beusch, Ahmet F. Coskun, Mohamed S. Abdel-Hakeem, R. Paul Johnson, Frank J. T. Staal, Vijayakumar Velu, Mirko Paiardini, Brandon F. Keele, Guido Silvestri, David Ezra Gordon, Jeffrey Alan Tomalka, Sheikh Abdul Rahman

This study shows that IL-6 restricts pre-thymic T cell lineage commitment in SIV-infected rhesus macaques, contributing to loss of viral control.

bioRxiv · Feb 2, 2026 · PreprintImmunology

Innate antiviral readiness drives the expansion of protective T stem cell memory against influenza

Ivan Tomic, David Ahern, Jeffrey Alan Tomalka, Alba Escalera, Teresa Aydillo, Matthew D. Pauly, Nadine Rouphael, Seema S. Lakdawala, Naseem Sadek, Elizabeth Clutterbuck, Nisha Singh, Parvinder K. Aley, Hannah Robinson, Spyridoula Marinou, Stephanie P. Hao, , Adriana Tomić

This study identifies innate antiviral readiness as a key driver of TSCM cell expansion, showing its predictive value for viral clearance and vaccine design.

bioRxiv · Dec 10, 2025 · PreprintImmunology

A combination TLR7/8 and RIG-I agonist adjuvant reverts asthmatic allergic sensitization and prevents aggravated influenza infection in OVA-sensitized mice.

Juan García-Bernalt Diego, Eleanor Burgess, Lauren A. Chang, M Prellberg, Moataz Noureddine, Naseem Sadek, Yong Chen, Farah El-Ayache, Gabriel Laghlali, Seok‐Chan Park, Vivian Yan, Pamela T. Wong, Bruno G. De Geest, Jeffrey Alan Tomalka, Michael Schotsaert

This study shows that combining TLR7/8 and RIG-I agonists prevents allergic sensitization and reduces influenza severity in OVA-sensitized mice.

bioRxiv · Jun 23, 2025 · PreprintImmunology