Author

Rutilio A. Fratti

University of Illinois Urbana-ChampaignORCID 0000-0001-9109-6666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 1 Organism:fungi (other)· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Jorge D. CalderiniD· 3 shared Charlie T. KnappiD· 2 shared Chi ZhangiD· 2 shared Daniel GrudzieniD· 2 shared Jahnavi M. KaratiD· 2 shared Razeen AhmediD· 2 shared Ved ShahiD· 2 shared Vito FaillaiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBiochemistry

Jorge D. CalderinORCID

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3 papers

Recent·Most cited

BiochemistryThe Journal of Cell BiologyPeer-reviewedOct 30, 2026

Yeast PI(3,4,5)P3 controls vacuole fusion through Vam7 and membrane microdomain assembly

Chi Zhang, Jorge D. Calderin, Vito Failla…·Rutilio A. Fratti

This study identifies PI(3,4,5)P3 as a regulator of yeast vacuole fusion, showing it controls vertex microdomain assembly and retains the SNARE Vam7 on membranes.

DOI 10.1083/jcb.202510232

yeastexperimental assay

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BiochemistryFrontiers in Cell and Developmental BiologyPeer-reviewedApr 29, 2026

Differential effects of lysophospholipid headgroups, acyl chain length and saturation on vacuole acidification, Ca2+ transport, and fusion

Chi Zhang, Yilin Feng, Jorge D. Calderin…·Rutilio A. Fratti

The paper examines how lysophospholipid headgroups and acyl chain properties affect yeast vacuole fusion, Ca2+ transport, and acidification.

2 citations

yeastexperimental assay

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MicrobiologyACS Infectious DiseasesPeer-reviewedMay 14, 2025

Broad-Spectrum Activity and Mechanisms of Action of SQ109 on a Variety of Fungi

Satish R. Malwal, Rocio Garcia‐Rubio, Milena Kordalewska…·Eric Oldfield

This study evaluates SQ109's antifungal activity against sixteen fungal pathogens and identifies its mechanisms involving mitochondrial targeting and isoprenoid biosynthesis pathway inhibition.

4 citations

yeastfungi (other)

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