Author

Fábio Hecht

University of Rochester MedicineORCID 0000-0001-9110-2587Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Brian James AltmaniD· 2 shared Isaac S. HarrisiD· 2 shared Joshua C. MungeriD· 2 shared Juliana CazariniD· 2 shared Stephano S. MelloiD· 2 shared A. M. Zakaria KhaniD· 1 shared Alexander MuiriD· 1 shared Aslihan Ambeskovic· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

Brian James AltmanORCID

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2 papers

Recent·Most cited

Cancer BiologyNaturePeer-reviewedMar 18, 2026

Catabolism of extracellular glutathione supplies amino acids to support tumor growth

Fábio Hecht, Marco Zocchi, Emily T. Tuttle…·Isaac S. Harris

This study shows that extracellular glutathione supports tumor growth by providing amino acids through catabolism, and inhibiting this process slows tumor growth.

28 citationstop 1%

humanexperimental assay

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Cancer BiologybioRxivPreprintAug 15, 2025

MYC and Epithelial to Mesenchymal Transition (EMT) Independently Predict Circadian Rhythm Disruption in Lung Adenocarcinoma

Jamison B. Burchett, Aslihan Ambeskovic, McKayla Ford…·Brian James Altman

This study identifies MYC expression and a mesenchymal cell state as independent predictors of circadian rhythm disruption in lung adenocarcinoma.

DOI 10.1101/2025.08.15.670530

humanbulk RNA-seq

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