Isaac S. Harris

This study identifies EGLN1 as essential for HCMV infection by mediating mitochondrial activation to increase dNTP pools required for viral DNA replication.

This study shows that extracellular glutathione supports tumor growth by providing amino acids through catabolism, and inhibiting this process slows tumor growth.

The paper develops predictive models using patient-derived breast cancer organoids to identify drug responses and guide new therapies for resistant disease.

This study identifies MYC expression and a mesenchymal cell state as independent predictors of circadian rhythm disruption in lung adenocarcinoma.