Joshua C. Munger

This study identifies EGLN1 as essential for HCMV infection by mediating mitochondrial activation to increase dNTP pools required for viral DNA replication.

This study shows that extracellular glutathione supports tumor growth by providing amino acids through catabolism, and inhibiting this process slows tumor growth.

This study identifies MYC expression and a mesenchymal cell state as independent predictors of circadian rhythm disruption in lung adenocarcinoma.

The paper introduces a CRISPR screening method called VIRCAA to identify genes affecting HCMV infection, finding JUNB as an anti-viral factor.

This study identifies the taurine-taurine transporter axis as a critical regulator of myeloid leukemia using temporal single-cell RNA-sequencing and functional experiments.

This study shows that SARS-CoV-2 main protease Nsp5 cleaves and inactivates TRMT1, a host tRNA modification enzyme, leading to reduced tRNA modifications and viral RNA levels in infected cells.

This study identifies the UL26-PIAS1 complex as a mechanism by which HCMV inhibits anti-viral gene expression and promotes cell-to-cell spread.