Author

Maria Paola Martelli

University of PerugiaORCID 0000-0001-9139-1729Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Adriano SettiiD· 1 shared Alessio Ferrari· 1 shared Alessio MengaiD· 1 shared Angela Maria SavinoiD· 1 shared Angelo D’AngeloiD· 1 shared Anna Mary Benedetti· 1 shared Brunangelo FaliniiD· 1 shared Chak Shun YuiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Adriano SettiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 19, 2026

TGS1 mediates mRNA 5'-cap trimethylation to promote oxidative phosphorylation in acute myeloid leukaemia.

Valentina Miano, Giovanna Carrà, Maxim Bouvet…·Isaia Barbieri

This study identifies TGS1 as a methyltransferase that modifies mRNAs encoding mitochondrial proteins in AML, promoting oxidative phosphorylation and cell survival, and shows its potential as a therapeutic target.

DOI 10.64898/2026.03.18.712389

humanexperimental assay

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BioinformaticsBiomoleculesPeer-reviewedJun 28, 2022

SiCoDEA: a simple, fast and complete app for analyzing the effect of individual drugs and their combinations

Giulio Spinozzi, Valentina Tini, Alessio Ferrari…·Maria Paola Martelli

SiCoDEA is an open-source app for analyzing drug effects and combinations, offering multiple models and visualization tools to assess synergy, antagonism, and additivity.

28 citations

proteomicsstatistical model

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