Author

Valentina Miano

University of CambridgeORCID 0000-0002-0260-5885Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1

Frequent Co-Authors

Isaia BarbieriiD· 2 shared Luca PandolfiniiD· 2 shared Adriano SettiiD· 1 shared Adrien LégeriD· 1 shared Alessio MengaiD· 1 shared Angela Maria SavinoiD· 1 shared Angelo D’AngeloiD· 1 shared Anna Mary Benedetti· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Isaia BarbieriORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 19, 2026

TGS1 mediates mRNA 5'-cap trimethylation to promote oxidative phosphorylation in acute myeloid leukaemia.

Valentina Miano, Giovanna Carrà, Maxim Bouvet…·Isaia Barbieri

This study identifies TGS1 as a methyltransferase that modifies mRNAs encoding mitochondrial proteins in AML, promoting oxidative phosphorylation and cell survival, and shows its potential as a therapeutic target.

DOI 10.64898/2026.03.18.712389

humanexperimental assay

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GenomicsNature CommunicationsPeer-reviewedDec 10, 2021

RNA modifications detection by comparative Nanopore direct RNA sequencing

Adrien Léger, Paulo Amaral, Luca Pandolfini…·Tony Kouzarides

The paper introduces Nanocompore, a method to detect RNA modifications using Nanopore direct RNA sequencing, validated on human polyA+ RNAs and non-coding RNAs.

420 citationstop 1%

humanlong-read sequencing

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