Cell BiologybioRxivPreprint
Hypomorphic NOTCH1 Expression Alters Cardiomyocyte Cellular Architecture in Hypoplastic Left Heart Syndrome
Jordann Lewis, Travis B. Lear, Brent Schlegel…·Anita P. Saraf
This paper uses CRISPR-edited human iPSCs with hypomorphic NOTCH1 to model hypoplastic left heart syndrome, identifying auranofin as a potential therapeutic.
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