Author

Anita P. Saraf

University of PittsburghORCID 0000-0001-7096-7418Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Jordann Lewis· 2 shared Aine N. Boudreau· 1 shared Amy Isabella SentisiD· 1 shared Basil Yaseen· 1 shared Bill B. CheniD· 1 shared Brent Schlegel· 1 shared Dhivyaa RajasundaramiD· 1 shared Dominic Woods· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Jordann Lewis

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2 papers

Recent·Most cited

Cell BiologyTherapeuticsPeer-reviewedJun 27, 2025

Novel 2D/3D Hybrid Organoid System for High-Throughput Drug Screening in iPSC Cardiomyocytes

Jordann Lewis, Basil Yaseen, Haodi Wu, Anita P. Saraf

The paper develops a 2D/3D hybrid organoid system for high-throughput drug screening in iPSC cardiomyocytes, validated using doxorubicin to assess cardiotoxicity and electrophysiological effects.

7 citations

humanorganoid / primary culture

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Cell BiologybioRxivPreprintSep 30, 2024

Hypomorphic NOTCH1 Expression Alters Cardiomyocyte Cellular Architecture in Hypoplastic Left Heart Syndrome

Jordann Lewis, Travis B. Lear, Brent Schlegel…·Anita P. Saraf

This paper uses CRISPR-edited human iPSCs with hypomorphic NOTCH1 to model hypoplastic left heart syndrome, identifying auranofin as a potential therapeutic.

1 citation

humanbulk RNA-seq

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