Author

Clifford A. Lowell

University of California, San FranciscoORCID 0000-0002-0467-7073Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Clare L. AbramiD· 3 shared Aafrin M. PettiwalaiD· 1 shared Alejandro Sweet-CorderoiD· 1 shared Alex Gia LeeiD· 1 shared Alexis J. CombesiD· 1 shared Bevin C. EnglishiD· 1 shared Catharina ConradiD· 1 shared Chester E. ChamberlainiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

Clare L. AbramORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Gain-of-function mutation in SKAP2 leads to type 1 diabetes and broader autoimmunity through hyperactive integrin signaling in myeloid cells

Courtney M. Tamaki, Chester E. Chamberlain, Clare L. Abram, Sumith Sundara Poojary, Jennifer Anne Bridge, Jennifer L. Matsuda, Whitney Tamaki, Niklas Rutsch, Lauren Spector, Wesley Dixon, Irina Proekt, Lisa R. Letourneau, Louis H. Philipson, Michael S. German, Mark Stuart Anderson, Clifford A. Lowell

bioRxiv · Apr 6, 2026 · PreprintImmunology

STING activation reshapes the tumor microenvironment leading to tumor regression in osteosarcoma

Elizabeth P. Young, Christine A. Johnson, Alex Gia Lee, Douglass Morris, Jessica L. Tsui, Marcus R. Breese, Juan A. Cámara, Courtney R. Schott, Clare L. Abram, Stanley G. Leung, Leanne C. Sayles, Aafrin M. Pettiwala, Vanessa S. Gutierrez Vera, Clifford A. Lowell, Alexis J. Combes, , Alejandro Sweet-Cordero

This study shows that activating the STING pathway in osteosarcoma leads to tumor regression and immune memory, suggesting it as a therapeutic target.

bioRxiv · Oct 24, 2025 · PreprintCancer Biology

Loss of neutrophil Shp1 produces hemorrhagic and lethal acute lung injury

Sayyed Farshid Moussavi-Harami, Simon J. Cleary, Mélia Magnen, Yurim Seo, Catharina Conrad, Bevin C. English, Longhui Qiu, Kristin M. Wang, Clare L. Abram, Clifford A. Lowell, Mark R. Looney

This study shows that loss of neutrophil Shp1 causes severe lung injury and death in mice, and that activating Shp1 can reduce inflammation and lung damage.

Journal of Clinical Investigation · Oct 1, 2024Peer-reviewedImmunology