Author

Lena Sapozhnikov

Weizmann Institute of ScienceORCID 0000-0001-9191-5115Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Eli AramaiD· 2 shared Akandé Rouchidane EyitayoiD· 1 shared Andreas BergmanniD· 1 shared Bertrand MollereauiD· 1 shared Catherine JamardiD· 1 shared Ehud SivaniD· 1 shared Florence Jollivet· 1 shared Gabriel IchimiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Eli AramaORCID

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2 papers

Recent·Most cited

Lipid droplets sequester cell death effectors and delay regulated cell death execution

Yingquan Shan, Kinga B. Stopa, Akandé Rouchidane Eyitayo, Florence Jollivet, Victor Girard, Catherine Jamard, Lena Sapozhnikov, Eli Arama, Judit Szécsi, Mohammed Bendahmane, Nathalie Davoust, Ludivine Walter, Mingyao Liu, Nicolas Aznar, Gabriel Ichim, Bertrand Mollereau

The paper shows lipid droplets delay regulated cell death by sequestering mitochondrial effectors like Bax, thereby reducing apoptosis execution in cancer and germ cells.

bioRxiv · Jul 13, 2026 · PreprintCell Biology

The Initiator Caspase Dronc Drives Compensatory Proliferation of Apoptosis-Resistant Cells During Epithelial Tissue Regeneration After Ionizing Radiation

Tslil Braun, Naama Afgin, Lena Sapozhnikov, Ehud Sivan, Andreas Bergmann, Luis Alberto Baena-López, Keren Yacobi-Sharon, Eli Arama

This study identifies Dronc-driven compensatory proliferation in Drosophila wing imaginal discs after ionizing radiation, revealing molecular mechanisms and interactions that maintain tissue regeneration balance.

Nature Communications · Dec 4, 2025Peer-reviewedDevelopmental Biology