Andreas Bergmann

AlphaFold3-based modeling uncovers the dynamic structural interface between full-length IAP antagonists and DIAP1 for apoptosis regulation in Drosophila

The paper uses AlphaFold3 to model the 3D structures of IAP antagonists and DIAP1, revealing structural interactions and mechanisms of apoptosis regulation in Drosophila.

Single-cell RNA analysis reveals unexpected hemocyte plasticity and immune cell specialization in a Drosophila overgrowth model

The paper uses single-cell RNA sequencing to analyze hemocyte diversity in Drosophila overgrowth models, identifying new plasmatocyte subtypes and plasticity under chronic apoptotic signaling.

The Initiator Caspase Dronc Drives Compensatory Proliferation of Apoptosis-Resistant Cells During Epithelial Tissue Regeneration After Ionizing Radiation

This study identifies Dronc-driven compensatory proliferation in Drosophila wing imaginal discs after ionizing radiation, revealing molecular mechanisms and interactions that maintain tissue regeneration balance.

AMP accumulation during mitochondrial stress induces transcription of cytosolic and mitochondrial protein synthesis components via NHR-180

The paper identifies NHR-180 as a regulator of mitochondrial function and protein synthesis that can restore mitochondrial function in atfs-1(null) worms and mammalian models.