Filipe De Vadder

OrganScaleR provides a Shiny tool for size-adjusted organ-weight analysis in mice, avoiding misleading ratios by using ANCOVA or causal mediation based on body-weight overlap.

This study examines the effects of semaglutide on growth and metabolism in juvenile mice, finding it lowers blood glucose in normally growing mice but worsens growth impairment in stunted juveniles.

This study shows that juvenile protein restriction in mice reduces sexual dimorphism by affecting somatic growth, energy metabolism, and hepatic molecular identity, with distinct adaptations in reproductive development.

This study shows that suboptimal refeeding diets can restore body length but impair glucose metabolism in male mice with early-life malnutrition, while optimal refeeding fully restores growth in females.

This study shows that a Western diet with protein restriction in juvenile mice causes metabolic dysregulation without obesity, including hyperglycemia and fatty liver.