Author

Sean M. McKenna

Oncode InstituteORCID 0000-0001-9197-5089Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Ben H McLoughliniD· 1 shared Chenlu ZhangiD· 1 shared Conor WilliamsiD· 1 shared Edith van der NoliD· 1 shared Eoin Martin ScanlaniD· 1 shared Femke J. BoxmaniD· 1 shared Inés Rabadán GonzáleziD· 1 shared Ivana DrienovskáiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

Ben H McLoughlinORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 15, 2026

Rational Design of a Photoactivated Fluorescent Probe for Thiol-ene Mediated Protein Labelling

Ben H McLoughlin, Conor Williams, Sean M. McKenna…·Rita Petracca

This paper introduces a photoactivated fluorescent probe, AbzSH, for selective alkene labelling in proteins and complex biological samples.

DOI 10.64898/2026.10.13.758905

proteomicsexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivPreprintSep 23, 2026

PROXINAUT: An Automation Platform for Rapid Hit-to-Degrader Discovery

Sean M. McKenna, Monika T. Gnatzy, Edith van der Nol…·Sebastian J. Pomplun

PROXINAUT automates hit-to-degrader discovery by integrating library screening with parallel synthesis, resulting in validated degraders with improved binding affinity.

DOI 10.64898/2026.09.22.753586

experimental assaydrug response / drug discovery

𝕏 PostBluesky