Michal Pravenec

This study quantifies protein expression in rat brains, identifies pQTLs, and links them to behavioral traits and human disorders.

This study constructs a rat pangenome from linked-read data to enhance variant discovery and genotype-phenotype mapping in recombinant inbred strains.

The paper presents an improved rat reference genome, mRatBN7.2, which enhances genomic, transcriptomic, and proteomics data mapping and identifies millions of genetic variations across rat strains.

The paper uses CAGE sequencing to identify alternative promoter usage in a rat model of hypertension, linking promoter shifts to insulin resistance and blood pressure.

The paper identifies a trans locus in rats that causes a protein length-dependent shift in translational efficiency, affecting cardiac hypertrophy and sarcomere protein stoichiometry.

The paper identifies Tti2 as a gene influencing both adult hippocampal neurogenesis and serum glucose levels using a rat genetic model.