Hiroshi M. Sasaki

This paper introduces Decode-PAINT, a method for high-resolution chromatin imaging, and demonstrates its application to study X chromosome structure in cells.

Crisscross polymerization of DNA-origami slats enables the creation of micron-scale structures with uniquely addressable nanoscale features.

SABER enables highly multiplexed and amplified detection of DNA and RNA in cells and tissues by using oligo-based probes with long DNA concatemers for sensitive fluorescent detection.

This paper describes a method for producing high-purity single-stranded DNA for various applications.

The paper uses super-resolution imaging and integrative modeling to achieve 10 kb resolution of chromosome folding.

OligoMiner designs genome-scale oligo FISH probes with customizable parameters and evaluates probe specificity using supervised learning, demonstrating scalability across model organisms.