Peng Yin

This paper introduces ACE, a method for high-plex protein imaging in thick tissues, reducing imaging time and enabling uniform signal amplification across tissue depths.

This paper introduces a method to create complex RNA nanostructures with over 100 unique components using dsRNA bricks, overcoming limitations of RNA scalability and stability.

The paper introduces ExRPath and 15ExMPath techniques to expand human brain tissue for nanostructure analysis, revealing amyloid nanoclusters associated with SARS-CoV-2 in COVID-19 patients.

This paper develops a human lymphoid follicle chip platform to model intramuscular mRNA vaccine responses, showing it can replicate immune responses to both naive and recall antigens.

This paper introduces Decode-PAINT, a method for high-resolution chromatin imaging, and demonstrates its application to study X chromosome structure in cells.

Crisscross polymerization of DNA-origami slats enables the creation of micron-scale structures with uniquely addressable nanoscale features.

The paper characterizes a synthetic coherent feed-forward loop (CFFL) in E. coli cell-free systems, showing it can repress background activity but is not effective as a temporal filter.

SABER enables highly multiplexed and amplified detection of DNA and RNA in cells and tissues by using oligo-based probes with long DNA concatemers for sensitive fluorescent detection.

This paper describes a method for producing high-purity single-stranded DNA for various applications.

This paper designs de-novo RNA-based translational repressors with multi-input logic capabilities for synthetic biology applications.