Chengguo Yao

The paper shows that U1 AMO disrupts U1 snRNP structure, leading to intronic premature cleavage and polyadenylation by affecting RNAPII interaction and transcription elongation.

This study shows that CFIm25 regulates human stem cell function through effects on RNA polymerase II occupancy and gene expression, independent of its role in mRNA polyadenylation.

This study identifies SRSF7 as a novel m6A regulator that promotes glioblastoma cell proliferation and migration through m6A methylation of specific target mRNAs.

This study identifies NIPBL's interaction with RNA and treacle in regulating pre-rRNA transcription and nucleolar organization.