Author

Yi Ran

Sun Yat-sen University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andy Peng XiangiD· 2 shared Chengguo YaoiD· 2 shared Qiumin FengiD· 2 shared Yanhui Deng· 2 shared Andreas J. R. HabenichtiD· 1 shared Axel ImhofiD· 1 shared Changjun Yin· 1 shared Christian WeberiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

Andy Peng XiangORCID

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3 papers

Recent·Most cited

Self-Reactive B Cells in Artery Tertiary Lymphoid Organs Encode Pathogenic High Affinity Autoantibody in Atherosclerosis

Chuankai Zhang, Xi Zhang, Yi Ran, Zhihua Wang, Liping Li, Shu Wang, Junjie Zheng, Yixin Zhang, Ting Sun, Yutao Li, Shu Lu, Mingyang Hong, Zhe Ma, Sabine Steffens, Michael Hristov, , Changjun Yin

The paper identifies self-reactive B cells in atherosclerosis-associated tertiary lymphoid organs that produce high-affinity autoantibodies contributing to disease progression.

bioRxiv · Jul 10, 2025 · PreprintImmunology

U1 AMO (antisense morpholino oligos) disrupts U1 snRNP structure to promote intronic PCPA (premature cleavage and polyadenylation)

Qiumin Feng, Zejin Lin, Yanhui Deng, Yi Ran, Andy Peng Xiang, Congting Ye, Chengguo Yao

The paper shows that U1 AMO disrupts U1 snRNP structure, leading to intronic premature cleavage and polyadenylation by affecting RNAPII interaction and transcription elongation.

bioRxiv · Feb 24, 2023 · PreprintMolecular Biology

CFIm25 regulates human stem cell function independently of its role in mRNA alternative polyadenylation

Yi Ran, Shanshan Huang, Junjie Shi, Qiumin Feng, Yanhui Deng, Andy Peng Xiang, Chengguo Yao

This study shows that CFIm25 regulates human stem cell function through effects on RNA polymerase II occupancy and gene expression, independent of its role in mRNA polyadenylation.

RNA Biology · May 1, 2022Peer-reviewedMolecular Biology