Jackson J. McGaughey

This paper establishes two mouse models of Oropouche virus-induced hepatitis, showing that Type I interferons control disease severity and that contemporary isolates are less pathogenic than historical strains.

This study characterizes Oropouche orthobunyavirus replication in neural cells and brain slices, showing cytokine production and providing a model for studying viral neuropathogenesis.

This study shows Oropouche virus infects human placenta tissues and trophoblast organoids, potentially causing adverse pregnancy outcomes through vertical transmission.

This study shows that vaccine strains of Rift Valley fever virus replicate less in placental tissues compared to wild-type strains, suggesting attenuation at the maternal-fetal interface.