Author

Piret Kleis

University of FreiburgORCID 0000-0001-9247-8842Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Assay:electronic health records· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Carola A. HaasiD· 4 shared Enya PascheniD· 4 shared Ute HäussleriD· 4 shared Andrea Djie-Maletz· 1 shared Andreas VlachosiD· 1 shared Christian BoehleriD· 1 shared Diego M. VieiraiD· 1 shared Katharina HeiningiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersNeuroscience

Carola A. HaasORCID

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4 papers

Recent·Most cited

NeuroscienceNeurobiology of DiseasePeer-reviewedMay 19, 2025

Long-term hippocampal low-frequency stimulation alleviates focal seizures, memory deficits and synaptic pathology in epileptic mice

Piret Kleis, Enya Paschen, Andrea Djie-Maletz…·Ute Häussler

4 citations

mouseelectronic health records

𝕏 PostBluesky

NeuroscienceBrain stimulationPeer-reviewedMar 1, 2024

Low frequency stimulation for seizure suppression: identification of optimal targets in the entorhinal-hippocampal circuit

Piret Kleis, Enya Paschen, Ute Häussler, Carola A. Haas

This study identifies presynaptic targets in the entorhinal-hippocampal circuit that effectively suppress seizures using low-frequency stimulation in a mouse model of MTLE.

4 citations

mouseelectronic health records

𝕏 PostBluesky

NeuroscienceBrainPeer-reviewedSep 7, 2023

On-demand low-frequency stimulation for seizure control: efficacy and behavioral implications

Enya Paschen, Piret Kleis, Diego M. Vieira…·Carola A. Haas

This study evaluates on-demand low-frequency stimulation for seizure control in a mouse model of mesial temporal lobe epilepsy, showing improved efficacy and no cognitive deficits.

18 citations

mouseelectronic health records

𝕏 PostBluesky

NeuroscienceBMC BiologyPeer-reviewedJan 14, 2022

In vivo characterization and application of a novel potassium channel-based optogenetic silencer in the healthy and epileptic mouse hippocampus

Piret Kleis, Enya Paschen, Ute Häussler…·Carola A. Haas

The paper develops and tests a novel optogenetic silencer, PACK, in healthy and epileptic mice, finding it effectively inhibits neuronal activity but causes side effects.

12 citations

mouseelectronic health records

𝕏 PostBluesky