NeuroscienceNeurobiology of DiseasePeer-reviewed
Long-term hippocampal low-frequency stimulation alleviates focal seizures, memory deficits and synaptic pathology in epileptic mice
4 citations
Author
Enya Paschen
University of FreiburgORCID 0000-0001-6323-3889Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2022-2025 · peak 2/yrCo-Author Collaboration Network
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Curved chords = mutual co-authorship5 papers
Recent·Most cited
- NeuroscienceBrain stimulationPeer-reviewed
Low frequency stimulation for seizure suppression: identification of optimal targets in the entorhinal-hippocampal circuit
Piret Kleis, Enya Paschen, Ute Häussler, Carola A. Haas
This study identifies presynaptic targets in the entorhinal-hippocampal circuit that effectively suppress seizures using low-frequency stimulation in a mouse model of MTLE.
4 citations - NeurosciencebioRxivPreprint
Probing hippocampal stimulation in experimental temporal lobe epilepsy with functional MRI
Niels Schwaderlapp, Enya Paschen, Pierre LeVan…·Carola A. Haas
This study investigates brain-wide responses to hippocampal electrical stimulation in a mouse model of mesial temporal lobe epilepsy using fMRI, finding that stimulation frequency, not amplitude, determines the extent of activation spread.
- NeuroscienceBrainPeer-reviewed
On-demand low-frequency stimulation for seizure control: efficacy and behavioral implications
Enya Paschen, Piret Kleis, Diego M. Vieira…·Carola A. Haas
This study evaluates on-demand low-frequency stimulation for seizure control in a mouse model of mesial temporal lobe epilepsy, showing improved efficacy and no cognitive deficits.
18 citations - NeuroscienceBMC BiologyPeer-reviewed
In vivo characterization and application of a novel potassium channel-based optogenetic silencer in the healthy and epileptic mouse hippocampus
Piret Kleis, Enya Paschen, Ute Häussler…·Carola A. Haas
The paper develops and tests a novel optogenetic silencer, PACK, in healthy and epileptic mice, finding it effectively inhibits neuronal activity but causes side effects.
12 citations