Author

Paul Lapios

Centre National de la Recherche ScientifiqueORCID 0000-0001-9251-1374Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 1 Assay:electronic health records· 1 Assay:protein structure· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

David PerraisiD· 2 shared Étienne HerzogiD· 2 shared Vincent Paget-BlanciD· 2 shared Anna‐Lena Bolender· 1 shared Christelle MartiniD· 1 shared Elena Katharina Schulz‐Trieglaff· 1 shared Esther MarzaiD· 1 shared F. Ulrich HartliD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

David PerraisORCID

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3 papers

Recent·Most cited

NeuroscienceNature CommunicationsPeer-reviewedDec 13, 2025

Cryo-correlative light and electron tomography of dopaminergic axonal varicosities reveals non-synaptic modulation of cortico-striatal synapses

Paul Lapios, Robin Anger, Vincent Paget-Blanc…·David Perrais

The paper uses cryo-correlative light and electron tomography to study dopamine and glutamatergic synaptosomes in the striatum of adult mice, revealing differences in vesicle organization and release readiness between the two types.

8 citations

mouseelectronic health records

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NeuroscienceNature CommunicationsPeer-reviewedJun 3, 2022

Synaptomic analysis of dopaminergic inputs reveal hub synapses in the mouse striatum.

Vincent Paget-Blanc, Marlene E. Pfeffer, Marie Pronot…·Étienne Herzog

The paper identifies hub synapses in the mouse striatum formed by dopaminergic inputs that connect with glutamatergic, GABAergic, and cholinergic synapses, revealing a new framework for studying neuromodulation.

53 citationstop 4%

mouseproteomics

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NeuroscienceThe EMBO JournalPeer-reviewedAug 19, 2021

Novel proteostasis reporter mouse reveals different effects of cytoplasmic and nuclear aggregates on protein quality control in neurons

Sonja Blumenstock, Elena Katharina Schulz‐Trieglaff, Anna‐Lena Bolender…·Irina Dudanova

The paper develops a mouse model with a proteostasis reporter to study how cytoplasmic and nuclear protein aggregates affect neuronal protein quality control in aging and disease.

26 citations

mouseprotein structure

𝕏 PostBluesky