Author

Sonja Blumenstock

University of California San DiegoORCID 0000-0002-8124-3295Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:mouse· 4 Approach:experimental assay· 3 Assay:imaging· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Assay:protein structure· 1

Frequent Co-Authors

Enida GjoniiD· 2 shared Irina DudanovaiD· 2 shared Rüdiger KleiniD· 2 shared Takaki KomiyamaiD· 2 shared Anna‐Lena Bolender· 1 shared Byung Kook LimiD· 1 shared Carmelo SgobioiD· 1 shared David Arakelyan· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Enida GjoniORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Complementary cortical and thalamic contributions to cell-type-specific striatal activity dynamics during movement

Enida Gjoni, Ram Dyuthi Sristi, H. C. Liu, Shahar Dror, Xinlei Lin, Keelin O’Neil, Oscar M. Arroyo, Sun Woo Hong, Hannah Kim, Jeffrey Liu, Sonja Blumenstock, Byung Kook Lim, Gal Mishne, Takaki Komiyama

The paper identifies cell-type-specific activity dynamics in striatal neurons during movement by analyzing cortical and thalamic inputs in mice.

Science Advances · Jan 28, 2026Peer-reviewedNeuroscience

Optogenetic restoration of neuron subtype-specific cortical activity ameliorates motor deficits in Huntington's Disease mice

Sonja Blumenstock, David Arakelyan, Nicholas Del Grosso, Sonja Schneider, Yufeng Shao, Enida Gjoni, Rüdiger Klein, Irina Dudanova, Takaki Komiyama

The paper shows optogenetic activation of VIP-INs in HD mice restores motor function by normalizing activity in VIP-INs and CSPNs.

bioRxiv · Feb 7, 2025 · PreprintNeuroscience

Novel proteostasis reporter mouse reveals different effects of cytoplasmic and nuclear aggregates on protein quality control in neurons

Sonja Blumenstock, Elena Katharina Schulz‐Trieglaff, Anna‐Lena Bolender, Kerstin Voelkl, Paul Lapios, Jana Lindner, Mark S. Hipp, F. Ulrich Hartl, Rüdiger Klein, Irina Dudanova

The paper develops a mouse model with a proteostasis reporter to study how cytoplasmic and nuclear protein aggregates affect neuronal protein quality control in aging and disease.

The EMBO Journal · Aug 19, 2021Peer-reviewedNeuroscience

Striatal seeding of protofibrillar alpha-synuclein causes cortical hyperreactivity in behaving mice

Sonja Blumenstock, Fanfan Sun, Petar Marinković, Carmelo Sgobio, Sabine Liebscher, Jochen Wolfgang Herms

This study shows that injecting alpha-synuclein fibrils into the striatum of mice leads to altered cortical neuron function and reduced inhibitory cells in the somatosensory cortex.

bioRxiv · Sep 28, 2020 · PreprintNeuroscience