Dysregulation of the actin cytoskeleton and FMRP causes polar body protrusion defects in human fragile X premutation and aged oocytes
Kelly McCarter, Madhura Deshpande, Phillip A. Romanski…·Jeannine Gerhardt
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Weill Cornell MedicineORCID 0000-0001-9256-6607Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Kelly McCarter, Madhura Deshpande, Phillip A. Romanski…·Jeannine Gerhardt
Suraj Rajendran, Matthew Brendel, Josue Barnes…·Iman Hajirasouliha
This paper develops BELA, a deep learning model for ploidy prediction in human blastocysts using time-lapse imaging, achieving an AUC of 0.76 on the Weill Cornell dataset.
Pegah Khosravi, Ehsan Mohamad Kazemi, Qiansheng Zhan…·Iman Hajirasouliha
This paper develops an AI system to assess human blastocyst quality using deep learning, achieving 98% accuracy and identifying clinical factors affecting pregnancy rates.
Rajiv C. McCoy, Louise J Newnham, Christian Simon Ottolini…·Alan H. Handyside
The paper identifies tripolar mitosis as a mechanism causing aneuploidy in human embryos and links it to maternal PLK4 genetic variants.