Ari Green

Paired CSF and blood scRNA/TCR-seq in treatment-naive MS shows a small set of expanded, cytotoxic CSF-enriched CD8+ clonotypes, two of which recognize EBV epitopes.

This study shows that remyelination protects neurons from DLK-mediated neurodegeneration by preventing apoptosis and inflammation in a mouse model of demyelination.

This study uses [18F]-SynVesT-1 PET to analyze synaptic density in aging and Alzheimer's Disease, finding associations with amyloid-beta, tau, and cognitive performance.

This study identifies a mechanism by which progranulin deficiency leads to mitochondrial hyperfusion and neuroinflammation in GRN-FTD, showing that targeting C3aR can restore mitochondrial integrity and reduce microglial activation.

This paper uses a biomedical knowledge network to predict drug-disease treatment pairs and prioritize drug repurposing candidates.