TMEM63A, associated with hypomyelinating leukodystrophies, is an evolutionarily conserved regulator of myelination
Julia Halford, Amanda J. Senatore, Sage Berryman…·Swetha E. Murthy
This study identifies TMEM63A as a critical regulator of myelination in the CNS, showing its role in oligodendrocyte function and linking its dysfunction to hypomyelinating leukodystrophies.