Author

Leland Hu

Mayo ClinicORCID 0000-0001-9282-7619Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alex J. SmithiD· 1 shared Dieter Henrik HeilandiD· 1 shared Dolores HambardzumyaniD· 1 shared Dustin Grief· 1 shared Emir Radkevich· 1 shared Haylye White· 1 shared Joel Richard GarbowiD· 1 shared Kaisha Garvin· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperCancer Biology

Alex J. SmithORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aquaporin-4 Regulates Edema, Sustains Astrocyte Differentiation, and Constrains Immunosuppressive Remodeling in Glioblastoma

Tanvi Joshi, Kaisha Garvin, Matthew J. Flick, Montserrat Puigdelloses Vallcorba, Mehek Dedhia, Zhihong Chen, R Rodríguez Roche, Emir Radkevich, Susana Isabel Ramos, Nadejda M. Tsankova, Nhan L. Tran, Leland Hu, Katherine B. Peters, Alex J. Smith, Dieter Henrik Heiland, Dolores Hambardzumyan

This study shows that AQP4 regulates edema, maintains astrocyte differentiation, and limits immunosuppressive changes in glioblastoma.

bioRxiv · Oct 26, 2026 · PreprintCancer Biology

2H MRI-based quantification of leucine uptake in glioblastoma multiforme

Samantha McClendon, Xia Ge, Kyu-Ho Song, Dustin Grief, Shannon P. Fortin Ensign, Vikram D. Kodibagkar, Leland Hu, Joel Richard Garbow, Scott C. Beeman

This paper uses 2H MRI to quantify leucine uptake in glioblastoma multiforme, showing it can detect tumor burden beyond contrast-enhancing margins and measure amino acid metabolism.

bioRxiv · Apr 23, 2025 · PreprintCancer Biology

Morphological Metrics of Magnetic Resonance Imaging of Glioblastoma as Biomarkers of Prognosis

Lee A. Curtin, Paula Whitmire, Haylye White, Maciej M. Mrugała, Leland Hu, Kristin R. Swanson

This study computes morphological metrics from MRI scans of glioblastoma patients to correlate with survival outcomes, finding significant associations with overall survival.

bioRxiv · Jan 29, 2021 · PreprintBioinformatics