Nadejda M. Tsankova

This study shows that AQP4 regulates edema, maintains astrocyte differentiation, and limits immunosuppressive changes in glioblastoma.

The paper maps R-loop landscapes in the developing human brain and shows their role in neural differentiation and gene expression programs.

This study identifies how GBM cells use Plexin-D1 and Plexin-B2 to gain mechanocompliance, enabling immune-silent invasion through tissue.

This study identifies cortical tension as a mechanical barrier that prevents premature neuronal differentiation during neurogenesis, showing that reducing it accelerates neuronal lineage commitment and differentiation.

This study identifies a shared infiltrative signature in glioblastoma at the resection margin using spatial multi-omics data and validates EGFR as a key marker.

This study creates a single-nucleus transcriptomic atlas of the human DLPFC across the lifespan, revealing three transcriptomic phases and ten age-related trajectories linked to neurodevelopmental and neurodegenerative disease risk.

The paper identifies a common flanking variant linked to increased meiotic stability at the FGF14-SCA27B repeat locus.

The paper profiles gene expression and chromatin accessibility in 45,549 cortical nuclei across 6 developmental timepoints to study cell fate determination and neuropsychiatric disease mechanisms.

This study investigates the 3D genome organization in human brain development, finding differences in compartment and loop domain formation between neurons and glia.

Drosophila larval optic lobe single-cell RNA-seq and pseudotime analysis define a near-complete medulla neuroblast temporal transcription factor series, with Eyeless and Dichaete acting as regulatory hubs.

The paper isolates and profiles cell types in human TLE samples, revealing dysregulated pathways and an immature glial phenotype.