Susana Isabel Ramos

This study shows that AQP4 regulates edema, maintains astrocyte differentiation, and limits immunosuppressive changes in glioblastoma.

The paper develops an integrative sequencing strategy to catalog NRXN1 isoforms across human brain tissues and hiPSC organoids, revealing cell-type-specific splicing patterns and therapeutic potential of ASO targeting.

This study identifies cortical tension as a mechanical barrier that prevents premature neuronal differentiation during neurogenesis, showing that reducing it accelerates neuronal lineage commitment and differentiation.

This study identifies a shared infiltrative signature in glioblastoma at the resection margin using spatial multi-omics data and validates EGFR as a key marker.