Joel Richard Garbow

Indirect Deuterium Displacement Exchange Imaging for Non-invasive High-Resolution CSF Production Mapping

This paper introduces a non-invasive MRI method to map CSF production in rats using deuterium oxide and validates it with pharmacological suppression.

2H MRI-based quantification of leucine uptake in glioblastoma multiforme

This paper uses 2H MRI to quantify leucine uptake in glioblastoma multiforme, showing it can detect tumor burden beyond contrast-enhancing margins and measure amino acid metabolism.

Evaluation of gliovascular functions of Aqp4 readthrough isoforms

This study evaluates the role of AQP4 readthrough isoforms in gliovascular functions using a novel mouse model and finds that AQP4x modulates BBB integrity and protein localization.

Distinct disease mutations in DNMT3A result in a spectrum of behavioral, epigenetic, and transcriptional deficits

This study examines how different DNMT3A mutations cause varied behavioral, epigenetic, and transcriptional issues in neurodevelopmental disorders.

A MYT1L Syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation

This paper develops a MYT1L syndrome mouse model that recapitulates human phenotypes, revealing disrupted brain development and neuronal maturation as underlying mechanisms.

Transient uterine hypercontractility causes fetal cerebral oxidative stress and enduring mitochondrial and behavioral abnormalities in adolescent male rat offspring

This study shows that transient placental ischemia-hypoxemia in pregnant rats causes oxidative stress and long-term mitochondrial and behavioral issues in male offspring.