Gary V. Désir

This paper introduces pan-ExM-t, an all-optical method for visualizing specific proteins in the ultrastructural context of brain tissue, demonstrating its application on various markers in mouse brain sections and neuron cultures.

This paper shows that renalase activates mitochondrial leak metabolism to enhance protein synthesis and protect cells from stress and injury.

This paper introduces MAPS, a deep-learning approach for automated segmentation of mitochondrial ultrastructure in 3D pan-ExM images, enabling high-throughput quantification of morphology and protein localization.