Author

Jeffrey M. LeDue

University of British ColumbiaORCID 0000-0001-9298-7305Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Timothy H. MurphyiD· 2 shared Brian A. MacVicariD· 1 shared Carlos Barrón· 1 shared Cheryl Lea WellingtoniD· 1 shared Christopher J. GroteniD· 1 shared Fabio M V RossiiD· 1 shared Federico BolañosiD· 1 shared Honor CheungiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Timothy H. MurphyORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintApr 27, 2023

Leveraging the power of 3D brain-wide imaging and mapping tools for brain injury research in murine models

Mehwish Anwer, Jeffrey M. LeDue, Zefang Wang…·Cheryl Lea Wellington

The paper describes a whole-brain imaging pipeline to study neuronal activity changes after traumatic brain injury in mice, finding reduced c-Fos cell density in injured brains.

1 citation

mousespatial transcriptomics

𝕏 PostBluesky

NeuroscienceCell ReportsPeer-reviewedOct 1, 2022

Quantitative fluorescence lifetime imaging uncovers a novel role for KCC2 chloride transport in dendritic microdomains

Nicholas L. Weilinger, Leigh E. Wicki‐Stordeur, Christopher J. Groten…·Brian A. MacVicar

The paper uses FLIM to map dendritic chloride ion levels and identifies KCC2's role in creating chloride microdomains, revealing implications for ischemic stroke.

27 citations

imagingexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 7, 2021

Dual brain cortical calcium imaging reveals social interaction-specific wide-spread correlated cortical activity in mice.

Nicholas J. Michelson, Federico Bolaños, Luis A. Bolaños…·Timothy H. Murphy

The paper uses calcium imaging to show that social interaction in mice causes widespread correlated cortical activity, which is specific to individual interactions and not just local touch.

3 citations

mouseimaging

𝕏 PostBluesky