Timothy H. Murphy

The paper evaluates video LLMs for automated behavioral segmentation and scoring in mice performing a water-reaching task, finding that Gemini 2.5 Pro achieves high accuracy with specific resolution and visibility requirements.

PyMouse Lifter reconstructs 3-D mouse poses from 2-D videos with minimal annotation, improving behavior classification over 2-D data.

This study identifies specific cortical representations of automatic movements like grooming in mice at both network and single-cell levels.

This study uses mesoscale calcium imaging in HD mice during a sensory-guided task to explore altered cortical activity and its behavioral implications.

This paper introduces Time-Varying RNNs (TV-RNNs) for early classification of neural activity sequences, showing improved accuracy and earlier detection compared to standard RNNs in mouse and human motor task data.

The paper introduces a closed-loop neurofeedback and movement feedback system for mice, showing improved performance and adaptation to rule changes in both neural activity and movement tasks.

The paper investigates state-dependent functional connectivity between cerebellar neurons and cortical networks in mice, revealing dynamic changes in connectivity patterns across brain states.

This study shows that traumatic brain injury disrupts functional connectivity in mice, with recovery and state-dependent changes in connectivity and theta power during stillness.

The paper describes a whole-brain imaging pipeline to study neuronal activity changes after traumatic brain injury in mice, finding reduced c-Fos cell density in injured brains.

The paper shows that pre-movement neural activity in mice contains structured dynamics that predict goal-directed actions, but not random ones, several seconds before movement.

This study uses a water-reaching task to identify early forelimb motor deficits and cortical activity changes in Huntington Disease mouse models.

This study examines altered cortical processing of sensory input in Huntington disease mouse models, finding increased LFP power and sensory signal spread in HD mice.

PyRodentTracks is an open-source system for tracking and analyzing rodent behavior using computer vision and RFID, showing high accuracy and flexibility in different experimental setups.

The paper uses calcium imaging to show that social interaction in mice causes widespread correlated cortical activity, which is specific to individual interactions and not just local touch.

The paper clusters stereotyped large amplitude cortical LFP events and reveals precise phase-locking in neuronal populations during anesthetized states.

This paper describes a real-time system for tracking mouse body movements using DeepLabCut and demonstrates movement-triggered optogenetic stimulation.

The paper shows that spontaneous activity in the developing rat cortex synchronizes sensorimotor networks before whisker stimulation evokes motor cortex activation.