Kyra Kerkhofs

This study shows RSV competes with host mRNAs for ribosomes without using host shutoff strategies, and avoids activating antiviral pathways that reduce cap-dependent translation.

This study shows RSV optimizes translational efficiency by increasing polysome formation and enhancing ribosome recruitment to AU-rich host and viral transcripts through the M2-1 protein.

The paper identifies a POLR3B variant causing mis-splicing and altered Pol III transcriptome, revealing La protein's role in reshaping small ncRNA profiles and identifying tRF-1/tRF-3 as biomarkers for POLR3 deficiency.

The paper shows that Tetrahymena thermophila's Mlp1, lacking the RRM1 domain, functions as a La protein and alters tRNA processing by stabilizing 3-trailers and preventing leader/trailer pairing.

ribofootPrinter provides a Python toolkit for analyzing ribosome profiling data, offering simplicity and adaptability for specialized needs.