Brian N. Mathur

This study investigates how chronic alcohol exposure affects the responsiveness of claustrum projection neuron subtypes to anterior cingulate cortex input in mice.

This study shows chronic alcohol exposure reduces GABAergic synapses and perineuronal nets on striatal fast-spiking interneurons, promoting increased ethanol consumption.

This study examines claustrum activation during four cognitive tasks using fMRI, finding bilateral activation during cognitive control phases and supporting the NICC model.

This paper shows that CRISPR-dCas9 systems can cause behavioral and cellular changes in mice even without targeting specific genes, highlighting the need for validation.

This study identifies the claustrum as a key initiator of task-dependent network states in cognitive control using fMRI and structural connectivity analyses.

The paper shows that estradiol, not testosterone, mediates stress susceptibility in male mice by modulating specific neural circuits, and brain delivery of estradiol prevents depression-like behaviors.

The paper identifies pathological claustrum activity and its influence on cognitive network processing in chronic pain patients.

This paper describes a method to rapidly create mouse models of human epilepsy variants using in utero prime editing, enabling the study of seizures in a clinically relevant timeframe.

This study identifies that rILN neurons projecting to the dorsal striatum signal during action initiation and reward acquisition, influencing task success in mice.

The paper identifies synaptic connections from the claustrum to multiple cortical regions, supporting network motifs involved in cognitive control.

This study uses fMRI to show the claustrum is functionally connected to cognitive networks and activates during cognitive tasks, independent of sensorimotor processing.

This study shows the claustrum is essential for reward acquisition in cognitively demanding tasks but not in simpler ones.