Jimena Andersen

This study uses human spinal cord organoids to model C9orf72 ALS, identifying early RNA splicing dysregulation and RBP network dysfunction as key features of the disease.

This study develops human spinal cord organoids and assembloids to model oligodendrocyte development and disease states, showing they recapitulate developmental signatures and cytokine-induced dysfunction seen in multiple sclerosis.

The paper describes a human assembloid model to study enterovirus pathogenesis, showing that different EVs cause muscle contraction loss through distinct cellular mechanisms.

This study uses human assembloids to investigate how CACNA1G gene variants affect thalamocortical pathway function in neuropsychiatric disorders.

The paper profiles midgestation human spinal cord cells at single-cell resolution, revealing early diversification of motor neurons and glial cell types.

The paper maps gene-regulatory dynamics in the developing human cerebral cortex using single-cell data, identifying key transcription factors and disrupted regulatory elements in ASD.