Mayuri Vijay Thete

The paper describes a human assembloid model to study enterovirus pathogenesis, showing that different EVs cause muscle contraction loss through distinct cellular mechanisms.

This study creates a human assembloid model of the ascending somatosensory pathway using pluripotent stem cells and demonstrates its functional connectivity and response to pain-related stimuli.

The paper develops an assembloid model of the human cortico-striatal-thalamic-cortical circuit to study its function and disease-related disruptions.

The paper uses CRISPR screens in human forebrain assembloids to identify NDD genes involved in interneuron generation and migration, revealing novel roles for the ER in migration.

This study uses human assembloids to investigate how CACNA1G gene variants affect thalamocortical pathway function in neuropsychiatric disorders.

This paper develops a scalable neural organoid platform using biocompatible polymers to prevent fusion, enabling drug and teratogen screening with over 2,400 cortical organoids.

This study investigates interneuron migration defects in Timothy syndrome using human forebrain assembloids and identifies pharmacological targets to rescue migration abnormalities.