Yuejia Liu

Deleting Piezo1 and Piezo2 together in mice weakens uterine contractions and prolongs labor; uterine and sensory-neuron deletions act additively, and knockout uteri show reduced Gja1 (connexin43).

This study identifies statins as effective in targeting chemoresistant pancreatic cancer by inhibiting cholesterol metabolism and protein glycosylation, showing clinical benefit in a phase 2 trial.

Single cell RNA sequencing reveals how adolescent sex hormones sculpt hypothalamic cell types required for mating behavior.

This study develops a high-throughput in vivo Perturb-seq platform to analyze gene function across diverse cell types in the brain and peripheral nervous system, identifying cell type-specific transcriptional networks.

The paper investigates how pubertal sex hormones regulate transcriptional changes in the medial preoptic area of mice during puberty, revealing sexually dimorphic gene regulatory networks.

The paper identifies and spatially defines transcriptionally distinct neuronal cell types in the mouse habenula and shows their conservation with zebrafish.