Li-Man Liu

This study identifies the ATP-gated P2x7 receptor as a key channel in type II auditory nerves, showing its role in hearing sensitivity and noise protection through efferent control mechanisms.

This study shows that potassium channel blockers can prevent and treat noise-induced hearing loss and cochlear synapse degeneration when administered before or after noise exposure.

This study shows that Cx26 heterozygous mutations increase hearing sensitivity and noise susceptibility, challenging the previous view of their harmlessness.

This study uses auditory evoked cortical potentials to detect early functional and cognitive declines in Alzheimer's disease mice, showing changes in peak amplitudes and latencies before clinical symptoms appear.

This study shows that elevated extracellular K+ causes inner hair cell ribbon synapse degeneration, similar to noise-induced synaptopathy, and suggests BK channels as a potential therapeutic target.

This study shows that MOC efferent nerves also innervate cochlear supporting cells, modulating gap junctions and affecting OHC electromotility, which impacts hearing sensitivity and noise protection.