Author

Charlotte Beaver

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Emanuel GonçalvesiD· 2 shared Fiona M. BehaniD· 2 shared Francesco IorioiD· 2 shared Kosuke YusaiD· 2 shared Mathew J. GarnettiD· 2 shared Rizwan Ahmad AnsariiD· 2 shared Sarah Harper· 2 shared Adam P. Butler· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersGenomics

Emanuel GonçalvesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Application of barcode sequencing to increase the throughput and complexity of Plasmodium falciparum genetic screening

Allan Muhwezi, Mehdi Ghorbal, Theo Sanderson, Maria Ivanova, Rizwan Ahmad Ansari, Sarah Harper, Wesley Wong, Reiner Schulte, Gareth Girling, Frank Schwach, Ellen Bushell, Charlotte Beaver, Oliver Billker, Julian C. Rayner

The paper uses barcoded P. falciparum gene knockouts with BarSeq to phenotype parasite life cycle traits at scale.

bioRxiv · Sep 5, 2024 · PreprintMicrobiology

Minimal genome-wide human CRISPR-Cas9 library

Emanuel Gonçalves, Mark Thomas, Fiona M. Behan, Gabriele Picco, Clare Pacini, Felicity R. Allen, Alessandro Vinceti, Mamta Sharma, David A. Jackson, Stacey Price, Charlotte Beaver, Oliver M. Dovey, David J. Parry-Smith, Francesco Iorio, Leopold Parts, , Mathew J. Garnett

The paper designs a smaller genome-wide CRISPR-Cas9 library with reduced size while maintaining sensitivity and specificity, enhancing its applicability in complex models.

Genome biology · Jan 21, 2021Peer-reviewedGenomics

Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting

Francesco Iorio, Fiona M. Behan, Emanuel Gonçalves, Shriram G. Bhosle, Elisabeth D. Chen, Rebecca Shepherd, Charlotte Beaver, Rizwan Ahmad Ansari, Rachel Pooley, Piers Wilkinson, Sarah Harper, Adam P. Butler, Euan A. Stronach, Julio Sáez-Rodríguez, Kosuke Yusa, Mathew J. Garnett

CRISPRcleanR reduces false positives in CRISPR-Cas9 screens by correcting gene-independent responses without assuming copy number status.

BMC Genomics · Aug 13, 2018Peer-reviewedBioinformatics