Author

Christoph Hoppe

Essen University HospitalORCID 0000-0001-9364-9201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Adrian D. PrinziD· 2 shared Georg Sebastian HönesiD· 2 shared Johannes KösteriD· 2 shared Lars Christian MoelleriD· 2 shared Yara Maria MachlahiD· 2 shared Ann-Kathrin Schörding· 1 shared Christian Markus LangeiD· 1 shared Christina WenzekiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

Adrian D. PrinzORCID

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2 papers

Recent·Most cited

ALK Inhibition Prolongs Survival in a Mouse Model of ALK-positive Anaplastic Thyroid Cancer

Yara Maria Machlah, Tim Brandenburg, Georg Sebastian Hönes, Sarah Theurer, Adrian D. Prinz, Christoph Hoppe, Feyza Cansiz, Jens Thomas Siveke, Johannes Hubertus Schulte, Jukka T. Kero, Hendrik J Undeutsch, Johannes Köster, Dagmar Fuehrer, Lars Christian Moeller

Thyroid · Dec 30, 2025Peer-reviewedCancer Biology

Extrahepatic effects of thyroid hormone and resmetirom override their beneficial hepatic effects in alcohol-associated liver disease in mice

Christoph Hoppe, Georg Sebastian Hönes, Adrian D. Prinz, Devon Siemes, Christina Wenzek, Susanne Camilla Grund, Ann-Kathrin Schörding, Yara Maria Machlah, Eveline Bruinstroop, David Laehnemann, Manuel Philipp, Karine Cécile Gauthier, Frédéric Flamant, Daniel Robert Engel, Hideo Andreas Baba, , Lars Christian Moeller

The paper shows that thyroid hormone and resmetirom have harmful extrahepatic effects in white adipose tissue that counteract their beneficial effects on the liver in alcohol-associated liver disease in mice.

bioRxiv · Oct 10, 2025 · PreprintPathology