Author

Grant J. Logan

The University of SydneyORCID 0000-0001-9365-342XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Ian E. AlexanderiD· 2 shared Ann-Maree Huang· 1 shared Anne Cao Le· 1 shared Arthur Richard KitchingiD· 1 shared Austin R. Nelson· 1 shared Daniel Koo Yuk Cheong· 1 shared Jane HsiiD· 1 shared Jon Zachary· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Ian E. AlexanderORCID

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2 papers

Recent·Most cited

ImmunologyJCI InsightPeer-reviewedJul 8, 2025

Treatment of anti-myeloperoxidase glomerulonephritis using recombinant deoxyribonuclease I is enhanced by adeno-associated virus gene therapy

Anne Cao Le, Virginie Oudin, Jonathan Dick…·Kim Maree O’Sullivan

This study shows that DNase I treatment reduces ecDNA-driven inflammation in MPO-ANCA GN, and gene therapy enhances its therapeutic effect by extending its half-life.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologyNature CommunicationsPeer-reviewedApr 19, 2025

Structural characterization of antibody-responses from Zolgensma treatment provides the blueprint for the engineering of an AAV capsid suitable for redosing

Mario Mietzsch, Jane Hsi, Austin R. Nelson…·ROBERT V. McKENNA

This study uses cryo-EM to analyze antibodies against AAV9 vectors, identifying residues that enable capsid engineering to avoid neutralization and allow redosing.

15 citationstop 2%

humancryo-EM

𝕏 PostBluesky