Author
The University of SydneyORCID 0000-0002-6213-5627Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Carmen Unzu, Amanda X. Chen, Liliana Mâncio-Silva…·Luk H. Vandenberghe
The paper evaluates a natural AAV capsid liver targeting motif in human hepatocytes using in vivo and in vitro models, showing its role in liver targeting and the impact of PEG on transduction.
Anne Cao Le, Virginie Oudin, Jonathan Dick…·Kim Maree O’Sullivan
This study shows that DNase I treatment reduces ecDNA-driven inflammation in MPO-ANCA GN, and gene therapy enhances its therapeutic effect by extending its half-life.
Mario Mietzsch, Jane Hsi, Austin R. Nelson…·ROBERT V. McKENNA
This study uses cryo-EM to analyze antibodies against AAV9 vectors, identifying residues that enable capsid engineering to avoid neutralization and allow redosing.
Marti Cabanes‐Creus, Sophia H.Y. Liao, Renina Gale Navarro…·Leszek Lisowski
This study evaluates AAV vectors in human liver explants under normothermic perfusion to assess their functionality and neutralization by human sera.