Alexander William Dowling

This paper demonstrates that sodium-calcium cross-talk regulates calcium oscillations in endothelial cells, which control angiogenic signaling and can be manipulated to generate angiogenic responses in engineered tissues.

This study uses optogenetics to control organ growth in Drosophila by manipulating calcium signaling, revealing how light intensity and timing affect organ size and tumor morphology.

The paper develops a Bayesian optimization framework to reverse-engineer morphogenesis by calibrating physics-based models to match experimental imaging data of Drosophila wing imaginal discs.