Author

Mitali Arun Tambe

Purdue University West LafayetteORCID 0000-0001-9389-2308Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1 Organism:zebrafish· 1

Frequent Co-Authors

Jean‐Christophe RochetiD· 2 shared Amandine BerthetiD· 1 shared Aswathy ChandraniD· 1 shared Aurélie de Rus JacquetiD· 1 shared Balazs G. Szoke· 1 shared Bobby G. NgiD· 1 shared Brian J. SpenceriD· 1 shared Bryce David Colon· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Jean‐Christophe RochetORCID

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3 papers

Recent·Most cited

NeuroscienceAntioxidantsPeer-reviewedJul 20, 2023

Protective effects of polyphenol-rich extracts against neurotoxicity elicited by paraquat or rotenone in cellular models of Parkinson's disease

Mitali Arun Tambe, Aurélie de Rus Jacquet, Katherine E. Strathearn…·Jean‐Christophe Rochet

The paper investigates the neuroprotective effects of polyphenol-rich extracts against paraquat and rotenone-induced neurotoxicity in Parkinson's disease models, identifying mechanisms involving antioxidant pathways and mitochondrial function.

26 citationstop 4%

experimental assay

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Developmental BiologybioRxivPreprintMay 23, 2021

A single heterozygous mutation in COG4 disrupts zebrafish early development via Wnt signaling

Zhi‐Jie Xia, Xin-Xin I. Zeng, Mitali Arun Tambe…·Hudson H. Freeze

The paper investigates how a COG4 mutation causes SWS by disrupting non-canonical Wnt signaling in zebrafish and fibroblasts, leading to developmental defects.

1 citation

zebrafishbulk RNA-seq

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NeuroscienceScientific ReportsPeer-reviewedNov 18, 2019

Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions

Gergely Tóth, Thomas Neumann, Amandine Berthet…·Lisa McConlogue

This study identifies small molecules that target the intrinsically disordered ensemble of α-synuclein, showing they can inhibit misfolding, restore phagocytosis, and block cellular transmission of α-synuclein.

26 citations

humanexperimental assay

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