Author

Aurélie de Rus Jacquet

Centre de recherche du CHU de Québec-Université LavalORCID 0000-0002-5548-8045Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:clustering· 1 Organism:mouse· 1

Frequent Co-Authors

Éric BoilardiD· 2 shared Floriane BretheauiD· 2 shared O.J. Arevalo· 2 shared Allison Yearwood· 1 shared Andrew L. LemireiD· 1 shared Arnaud DroitiD· 1 shared Aswathy ChandraniD· 1 shared Bastien Jacquet· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersNeuroscience

Éric BoilardORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Blood-brain barrier model architecture shapes peripheral immune cell trafficking in Parkinson's disease

Oceane Martinez, Lucile Gentile, Floriane Bretheau, Allison Yearwood, O.J. Arevalo, Flávia Natale Borba, Martine Boutin, Éric Boilard, Kelvin C. Luk, Francesca Cicchetti, Aurélie de Rus Jacquet

This study compares how different BBB models affect immune cell trafficking in PD, showing that model architecture significantly influences results.

bioRxiv · Jun 9, 2026 · PreprintNeuroscience

Parkinson's disease risk factors are expressed at brain barriers.

Floriane Bretheau, O.J. Arevalo, Vincent Gélinas, Louise Réveret, Océane Martinez, Marlie Ali Yandza, Bastien Jacquet, Léa Ferreira, Morgan Bérard, Charles Joly-Beauparlant, Steve Lacroix, Éric Boilard, Benoît Laurent, Frédéric Calon, Martin Parent, , Aurélie de Rus Jacquet

This study identifies Parkinson's disease risk genes expressed at brain barriers and shows poor transcript-protein correlation and low interspecies conservation.

bioRxiv · Oct 20, 2025 · PreprintNeuroscience

Protective effects of polyphenol-rich extracts against neurotoxicity elicited by paraquat or rotenone in cellular models of Parkinson's disease

Mitali Arun Tambe, Aurélie de Rus Jacquet, Katherine E. Strathearn, Jennifer A. Hensel, Bryce David Colon, Aswathy Chandran, Gad G. Yousef, Mary H. Grace, Mário G. Ferruzzi, Qingli Wu, James Edward Simon, Mary Ann Lila, Jean‐Christophe Rochet

The paper investigates the neuroprotective effects of polyphenol-rich extracts against paraquat and rotenone-induced neurotoxicity in Parkinson's disease models, identifying mechanisms involving antioxidant pathways and mitochondrial function.

Antioxidants · Jul 20, 2023Peer-reviewedNeuroscience

The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson's disease

Aurélie de Rus Jacquet, Jenna L Tancredi, Andrew L. Lemire, Michael C. DeSantis, Weiping Li, Erin K. O’Shea

eLife · Sep 30, 2021Peer-reviewedNeuroscience