Sympathetic neuron-derived NPY protects from obesity by sustaining the mural progenitors of thermogenic adipocytes.
Yitao Zhu, Lu Yao, Ana Luisa Gallo-Ferraz, Bruna Bombassaro, Marcela Reymond Simoes, Ichitaro Abe, Jing Wen Chen, Gitalee Sarker, Alessandro Ciccarelli, Linna Zhou, Carl Lee, Davi Sidarta-Oliveira, Noelia Martínez‐Sánchez, Michael Loran Dustin, Cheng Zhan, , Ana Isabel Domingos
This study shows that sympathetic neuron-derived NPY sustains mural progenitors of thermogenic adipocytes, protecting against obesity by maintaining thermogenic capacity.
Nature · Aug 28, 2024Peer-reviewedPhysiology