Dean Philip John Kavanagh

This study identifies Galectin-9 as a driver of venous thrombo-inflammation, linking inflammation to thrombus formation through platelet activation and NETosis.

This study shows that myocardial injury leads to pulmonary microvascular damage driven by neutrophils and S100A8/A9, which can be reduced by inhibiting S100A8/A9.

This study shows that Syk inhibition reduces hemin-induced thromboinflammation and improves perfusion in the lungs and kidneys of sickle cell mice.

This study identifies discrete inflammatory signatures driving thrombosis in the spleen and liver after Salmonella infection, revealing both organ-specific and shared mechanisms.

This study shows that DNT-2 and its receptors Toll-6 and Kek-6 regulate structural plasticity in dopaminergic circuits in Drosophila, affecting behavior and connectivity.